This study aimed to investigate the effect of silicon (Si) on the reduction of brown spot severity (BSS), caused by Bipolaris oryzae, and grain discoloration in several rice genotypes. An experiment was conducted in a greenhouse where eight genotypes were evaluated for their response to Si rates and decrease on BSS. The relationship between Si rates and BSS was linear negative. Additionally, a field experiment was conducted including forty-eight genotypes which were grown in upland conditions and evaluated for their response to Si rates and reduction on grain discoloration. The relationship between Si rates and grain discoloration was quadratic negative. Weight of filled grains per panicle increased as the Si rates in the soil increased. Genotypic differences for Si concentration in husk were evident for both non-amended and Si-amended plots. While the Si concentration in husk increased to all genotypes, there was no relationship between grain discoloration and Si concentration in husk for plants from non-amended and Si-amended plots. The genotype CAN-7024 with the highest resistance to leaf brown spot also showed the lowest grain discoloration in comparison to the genotypes Casado and Caqui.